Joell J Gills Selected Research

Nelfinavir (Viracept)

1/2021	Nelfinavir Inhibits the Growth of Small-cell Lung Cancer Cells and Patient-derived Xenograft Tumors.
1/2021	Combining Nelfinavir With Chloroquine Inhibits In Vivo Growth of Human Lung Cancer Xenograft Tumors.
9/2014	A phase I trial of the HIV protease inhibitor nelfinavir in adults with solid tumors.
1/2008	Nelfinavir, a new anti-cancer drug with pleiotropic effects and many paths to autophagy.
9/2007	Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo.

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Joell J Gills Research Topics

Disease

25	Neoplasms (Cancer) 10/2022 - 04/2002
6	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2017 - 07/2005
5	Lung Neoplasms (Lung Cancer) 01/2021 - 02/2004
4	Carcinogenesis 08/2013 - 07/2004
3	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2021 - 07/2005
2	Breast Neoplasms (Breast Cancer) 09/2007 - 03/2006
1	Adenomatous Polyps 01/2020
1	Polyps 01/2020
1	Triple Negative Breast Neoplasms 10/2017
1	Type 2 Diabetes Mellitus (MODY) 09/2013
1	Sarcoma (Soft Tissue Sarcoma) 03/2009
1	Waldenstrom Macroglobulinemia (Macroglobulinemia) 03/2009
1	HIV Infections (HIV Infection) 01/2008
1	Starvation 09/2005
1	Colonic Neoplasms (Colon Cancer) 04/2002

Drug/Important Bio-Agent (IBA)

6	Phosphatidylinositols (Phosphatidylinositol)IBA 07/2011 - 02/2006
5	Nelfinavir (Viracept)FDA Link 01/2021 - 09/2007
4	Biomarkers (Surrogate Marker)IBA 01/2021 - 09/2007
4	Pharmaceutical PreparationsIBA 09/2013 - 09/2007
4	CarcinogensIBA 08/2013 - 07/2005
4	LipidsIBA 07/2011 - 03/2006
4	Ether (Diethyl Ether)IBA 07/2011 - 03/2006
3	HIV Protease InhibitorsIBA 09/2014 - 09/2007
3	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 07/2011 - 03/2006
3	TOR Serine-Threonine KinasesIBA 09/2007 - 09/2005
2	Immune Checkpoint InhibitorsIBA 10/2022 - 01/2021
2	Sirolimus (Rapamycin)FDA Link 10/2017 - 02/2014
2	Metformin (Glucophage)FDA LinkGeneric 09/2013 - 08/2013
2	Phosphotransferases (Kinase)IBA 01/2008 - 02/2004
2	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 09/2007 - 09/2005
2	Biological ProductsIBA 05/2006 - 07/2005
2	Ornithine Decarboxylase (Decarboxylase, Ornithine)IBA 05/2006 - 01/2006
1	Chloroquine (Aralen)FDA LinkGeneric 01/2021
1	N-(3,4,5-trichlorophenyl)succinimideIBA 01/2020
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 10/2017
1	olaparibIBA 10/2017
1	Pemetrexed (MTA)FDA Link 02/2014
1	Thymidylate SynthaseIBA 02/2014
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 08/2013
1	Insulin (Novolin)FDA Link 08/2013
1	Insulin-Like Growth Factor I (IGF-1)IBA 08/2013
1	Insulin ReceptorIBA 08/2013
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 08/2013
1	OligonucleotidesIBA 07/2011
1	2- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA 07/2011
1	Glucose (Dextrose)FDA LinkGeneric 04/2009
1	Inositol (Myoinositol)IBA 04/2009
1	perifosineIBA 03/2009
1	AMP-Activated Protein KinasesIBA 01/2008
1	Ritonavir (Norvir)FDA Link 01/2008
1	Saquinavir (Invirase)FDA Link 01/2008
1	TensinsIBA 09/2007
1	Investigational DrugsIBA 09/2007
1	Antineoplastic Agents (Antineoplastics)IBA 09/2007
1	Growth Factor ReceptorsIBA 09/2007
1	PTEN Phosphohydrolase (PTEN Phosphatase)IBA 09/2007
1	sulforaphaneIBA 05/2006
1	anthraceneIBA 05/2006
1	EnzymesIBA 01/2006
1	Laminin (Merosin)IBA 09/2005
1	Imatinib Mesylate (Gleevec)FDA Link 09/2005
1	4- (N- methyl- N- nitrosamino)- 1- (3- pyridyl)- 1- butanoneIBA 07/2005
1	Nicotine FDA Link 07/2005
1	SmokeIBA 07/2005
1	WithanolidesIBA 08/2004
1	ResveratrolIBA 08/2004
1	ixocarpalactone AIBA 08/2004
1	StilbenesIBA 08/2004
1	4'-bromoflavoneIBA 08/2004
1	NAD(P)H Dehydrogenase (Quinone) (Quinone Reductase)IBA 08/2004
1	deguelinIBA 08/2004
1	brassininIBA 08/2004
1	isoliquiritigenin (GU 17)IBA 08/2004
1	bruceantinIBA 08/2004
1	FlavanonesIBA 08/2004
1	FlavonesIBA 08/2004
1	Cyclooxygenase 1IBA 08/2004
1	flavanoneIBA 08/2004
1	FlavonoidsIBA 08/2004
1	EstersIBA 04/2002
1	tithofolinolideIBA 04/2002
1	LactonesIBA 04/2002
1	tirotundinIBA 04/2002
1	2-hydroxytirotundinIBA 04/2002
1	SesquiterpenesIBA 04/2002
1	3-acetoxydiversifololIBA 04/2002
1	tagitininIBA 04/2002
1	ethyl acetateIBA 04/2002
1	AcidsIBA 04/2002

Therapy/Procedure

8	Therapeutics 01/2011 - 02/2004
4	Drug Therapy (Chemotherapy) 01/2021 - 09/2005
2	Chemoprevention 08/2013 - 08/2004
1	Fecal Microbiota Transplantation 10/2022
1	Immunotherapy 10/2019
1	Radiotherapy 10/2017